Life Sciences Project Management (part of the LSPM Group) is led by Daniel B. DeOliveira, PhD, PMP; a Senior Scientific and Drug Discovery and Development Project Leader/Manager with extensive expertise (20+ years) in leading Internal and External (CRO/CMO) Project teams and in Project Management experience.

Our specialty is in Peptides, Peptidomimetics, Small Molecules, Biologics and Bioconjugates based drug discovery & development; we specialize in designing, producing, validating and developing products for use as therapeutics, high-affinity ligands, and for studying biological models and processes. Successful managing domestic and international teams to bring programs from early, mid, and late stage Research to successful pre-clinical end-point. Effective at Team Building and enabling cross-functional teams to work Efficiently and Collaboratively. Also experienced in Alliance and CRO Management.

Extensive experience in the Development of Peptides, both as a traditional API as well in the more  complex sector of Neoantigen mediated Personalized Medicine for both cancer vaccines and autologous cell therapy. Experienced in devising, building, and leading GMP and GxP manufacturing campaigns.

Life Sciences Project Management is focused on advising and assisting organizations in delivering Life Science Programs. We provide Project Management Consulting services on Drug Discovery; specializing in Peptide and Peptidomimetics, Small Molecules, Biologics and Biological Conjugates, from early, mid, and late stage Drug Discovery to a successful pre-clinical end-point (IND enabling studies: Safety and Tox.)

Several years of experience in the Technical Operations and logistics aspects of managing a Personalized-Medicine clinical trial and ensuring patient-segregation from start to finish. From the initial donation of patient-specific material at the clinical site, to time-critical shipment via appropriate temperature control to the CMO, managing various steps of the manufacturing process at several different CMOs using patient dedicated suites and or manufacturing lanes, followed by shipment back to the clinical site for dosing to that one patient. All activities have to be closely monitored and have appropriate quality controls via COI/COC to ensure patient safety.

Disease Area Focus: Immuno-Oncology, Oncology, Endocrinology, Metabolic and Rare Diseases.

Clinical Modalities: Traditional API (peptide and small molecule), Radio-Theranostics (Nuclear Medicine), Personalized Cancer Vaccines and Autologous Cell Therapy.

Click here for Daniel B. DeOliveira’s LinkedIn profile; or please visit our LinkedIn Company page

 

Drug Discovery Experience includes:

  • Oncology and Endocrinology Drug Discovery Experience
  • Nuclear Medicine, Radio-Theranostics & PRRT
  • Peptide and small molecule Medicinal Chemistry
  • Compound Design & Synthesis
  • SAR Analysis & Receptor profiling
  • Hit-to-Lead Medicinal Chemistry
  • Lead Optimization
  • Candidate selection to FIM (First In Man)
  • In-vitro binding and bioactivity assays
  • In-vivo modeling and efficacy
  • Pharmacokinetics, drug metabolism and stability
  • Formulation & analytical method development

Project Management Experience includes:

  • Extensive Drug Discovery Project Leadership experience
  • Internal & External (CRO/CMO) Research Project management
  • Leading and managing GMP manufacturing campaigns
  • Technical Operations and Logistics aspects of a personalized-medicine clinical trial
  • Preparing Drug Substances sections in IND application 
  • Coordinate communication with Stakeholders & with KOLs
  • Alliance Management
  • Patent applications; inventor on multiple issued patents
  • Extensive Personnel Management (matrix and functional)
  • Track Deliverables and KPIs
  • Track and Maintain Budgets
  • Identify, Manage and Mitigate Risk
  • Resources Identification,  Allocation and Management
  • Mentor & Develop Group Members

Specialties: Project Management, PMP (Project Management Professional) Certified,  Team building, Collaborative Team based approach to problem solving, Mentoring, Medicinal chemistry, Rational Drug Design, Peptide Drug Discovery, Radio-Theranostics, Peptide-Drug Conjugates.